Who will take the final two steps in 2025 NCAA Tournament bracket? Our best Final Four March Madness predictions are in and they're right here

Cooper Flagg's point total is sky-high for this battle of No. 1 seeds when you consider what the Houston Cougars defense can do to the Duke Blue Devils attack, per Jason Logan's Final Four picks.

CBS Sports and TNT Sports will combine to provide live coverage of all 67 games from the 2025 NCAA Tournament. Basketball competition officially tipped Tuesday night on truTV with the First Four contested in Dayton, Ohio and concludes with the NCAA Championship Game April 7 in San Antonio on CBS.

If Duke wins it all, one bettor could turn a $5, five-leg parlay into a huge payday, complementing the $20k they've already made. Patrick Everson has the scoop.

There are no real edges for any of these teams as the matchups fit their playing styles. Duke and Houston have the two best defenses in the country and play slower, so fitting they meet, while Auburn and Florida both play at quicker tempos and rank as the second and third-best offenses behind Duke.

The Huskies are significant favorites to win the women’s Final Four after taking down USC on Monday night in the Elite Eight. UConn is -130 at BetMGM to win its 12th national title and first since 2016.

Final Four picks, predictions, odds for Duke Blue Devils vs Houston Cougars NCAA Tournament March Madness game Saturday, April 5, 2025. Who wins game?

Winning March Madness is one of the hardest things to do in sports. After playing a full four-month regular season from November through March, a team must win at least six pressure-packed NCAA Tournament games against some of the best basketball schools in the country.

What are Final Four odds now? What to know about Houston Cougars vs Duke Blue Devils point spread, moneyline, over/under for March Madness betting.