NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco 49ers and Buffalo Bills.

Bills' QB Josh Allen is the current favorite for MVP. Expectations aren't something I like to make a habit. However, it's hard not to expect the best from Allen and the Bills this week. Beating the Chiefs the way they did helped them check off that confidence box, and they did it on their 12th straight week of football.

Thanksgiving week means two things for the 2024 NFL schedule. First, after six teams were on a bye, the Week 13 slate is back to a full 16 games until it drops down again next week.Second, there's a lot of great action to enjoy from a Thursday tripleheader to Monday night as the calendar also flips from November to December.