The Buffalo Bills can clinch their fifth straight AFC East title with a win over the San Francisco 49ers on Sunday night. To ...

After games on both Thanksgiving and Black Friday, the NFL caps off the Sunday slate with the Buffalo Bills hosting the San ...

The Buffalo Bills will host the San Francisco 49ers at Highmark Stadium in Orchard Park, New York, on Sunday, December 1, at ...

Running back Christian McCaffrey says the 49ers are “hungry” to make a playoff push even with the defending NFC champions ...

Buffalo Bills linebacker Matt Milano is expected to see NFL action on Sunday for the first time since October 2023. The Bills have activated Milano ...

Let's go back to week 7 of the 2024 NFL season. The post Brandon Aiyuk Shares Positive Injury Update While Kyle Shanahan and ...

Analyzing Sunday’s San Francisco 49ers at Buffalo Bills odds and lines, with expert NFL picks and predictions.

The San Francisco 49ers and Buffalo Bills are set to face-off in the Week 13 edition of Sunday Night Football. Before the season began, this matchup was circled ...

A snowstorm in Buffalo is still wreaking havoc on Highmark Stadium less than 24 hours before the Bills' scheduled matchup ...

Police officers used pepper spray to break up an on-field brawl between Ohio State and Michigan football players Saturday in ...

They don't get a divisional opponent in Week 13, but a struggling San Francisco 49ers team still possesses plenty of firepower for Buffalo to be concerned with as it starts December. Here are five ...

The Buffalo Bills will look to clinch the AFC East on Sunday with a win against the San Francisco 49ers in what's expected to ...