It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian McCaffery and Deebo Samuel?

McCaffrey suffered a potentially season-ending PCL injury, 49ers coach Kyle Shanahan said after the 35-10 loss to the Bills.

Whereas New York Jets fans have little to celebrate, their rival fans in the AFC East might be celebrating a little too much.

Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...

Christian McCaffrey was tearing it up against the Bills before exiting early in the second quarter with a knee injury.

The return of a superstar may be short lived. It was a snowy night in Buffalo, New York when the San Francisco 49ers took on ...

Kyle Shanahan said that Christian McCaffrey did injure his PCL and it is a 6-week recovery. His season now looks like it’s ...

SANTA CLARA, CALIFORNIA - JANUARY 22: Christian McCaffrey #23 of the San Francisco 49ers rushes for a touchdown against the ...

In the 49ers' Week 13 game against the Buffalo Bills, McCaffrey suffered a PCL (posterior cruciate ligament) injury in his ...

The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...

The 49ers are down to one healthy RB, rookie Isaac Guerendo. They will likely elevate Patrick Taylor Jr. from the practice ...