Neil Reynolds, Jeff Reinebold and Phoebe Schecter discuss San Franciscos playoff prospects on the Inside The Huddle Pofcast; ...

While making updates to the team’s injury report, the San Francisco 49ers announced that left tackle Trent Williams will miss ...

Three things I’m pondering as the Bills return from their bye for the stretch run… Mila-No More Waiting Matt Milano is ...

It’s not like he was throwing at game speed, but the sight of Brock Purdy throwing the ball during warmups Friday was ...

Defensively, two of the 49ers’ best players this season are out and will not travel as defensive end Nick Bosa (obliques, ...

The San Francisco 49ers are on the verge of falling out of contention for a playoff spot in the NFC after consecutive losses ...

First comes Brock Purdy, the team's star quarterback, who missed Week 12 with a right shoulder. While Purdy is still ...

The San Francisco 49ers released their latest injury updates headed into the team's Week 13 matchup vs. the Buffalo Bills.

Brock Purdy is expected to return Sunday night against the Bills, but offensive tackle Trent Williams, defensive end Nick ...

The San Francisco 49ers are up against the Buffalo Bills in Week 13. The 49ers have dealt with an array of injuries this ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

It seems like Trent Williams will miss his second game in a row this weekend with an ankle injury. Williams didn't practice ...