McCaffrey suffered a potentially season-ending PCL injury, 49ers coach Kyle Shanahan said after the 35-10 loss to the Bills.

Denver Broncos wide receiver Jerry Jeudy's first catch in Denver as a visitor goes for a 44-yard gain.

Whereas New York Jets fans have little to celebrate, their rival fans in the AFC East might be celebrating a little too much.

The 2024 season hasn’t gone as hoped, but it’s unfair to pin the blame on Purdy. The Niners built a top-heavy roster that is ...

Fans were in disbelief that Josh Allen indirectly threw a touchdown pass to himself in Sunday's game against the San Francisco 49ers. Even the Buffalo ...

The Great Lakes region saw new snow Monday and faced the prospect of even more this week after U.S. travelers battled harsh ...

Cleveland Browns kicker Dustin Hopkins misses a field goal for the seventh time in 2024.

San Francisco 49ers star running back Christian McCaffrey suffered a PCL injury and is expected to miss six weeks, head coach ...

The San Francisco 49ers are preparing for rookie running back Isaac Guerendo to take on the primary ball-carrying duties for ...

The rivalry between Eli Manning and Tom Brady continues to rage after the Giants legend commented on the Patriots great's ...

The 49ers’ goal last offseason was to strengthen their depth in pursuit of another NFC crown. That depth has been tested and ...

The Buffalo Bills clinched their record fifth consecutive AFC East title Sunday night after defeating the 49ers 35-10 on ...