Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

Dealing with injuries to Christian McCaffrey and Jordan Mason at running back, the 49ers have made a move at the position.

Kyle Shanahan addressed the possibility of Christian McCaffrey returning for the playoffs, if the 49ers make it.

The San Francisco 49ers on Wednesday continued adjusting to life without running backs Christian McCaffrey and Jordan Mason.

Slow motion video shows where 49ers running back Christian McCaffrey seemingly injured himself and ended his season.

The San Francisco 49ers return to Levi's Stadium to face the Chicago Bears. This matchup marks the 70th all-time meeting ...

Christian McCaffrey's injury against the Bills could be due to the heavy workload he received since returning to the 49ers.

The San Francisco 49ers could say goodbye to RB Jordan Mason, one of their most productive offensive players, in the near ...

The San Francisco 49ers are moving forward without star running back Christian McCaffrey or backup Jordan Mason for the ...

The San Francisco 49ers are falling behind the Seattle Seahawks in the NFC West. Losers of three consecutive contests, it was ...

49ers head coach Kyle Shanahan told reporters Monday that McCaffrey suffered a posterior cruciate ligament (PCL) injury ...

A spate of injuries has derailed the 49ers' Super Bowl hopes his season, but the bigger question is if their title window has ...